Global Gene Therapy Market Size & Trends Report Segmented by Type (Gene Silencing, Cell Replacement, Gene Augmentation), Vector (Viral, Non-viral), Therapeutic Area, Route of Administration (Intravenous), & Regional Forecasts to 2029
The global gene therapy market is projected to grow at a significant CAGR of 20% from 2024 to 2029. This growth is driven by advancements in gene-editing technologies, a surge in research funding, an increasing prevalence of genetic disorders, and rising demand for personalized medicine. However, high costs associated with gene therapies and limited accessibility in developing regions pose restraints to market growth. To learn more about the research report, download a sample report.
Report Overview
Gene therapy is a medical approach that involves modifying or replacing defective genes to treat or prevent diseases. This therapy can use techniques such as inserting a functional gene, deactivating a faulty gene, or repairing mutated genes. It targets the underlying genetic causes of diseases, providing potential cures rather than just managing symptoms. Gene therapy is being explored for a wide range of conditions, including genetic disorders, certain cancers, and chronic diseases like haemophilia or sickle cell anaemia.
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Addressing Genetic Disorders: The Key Driver of Gene Therapy Market Growth
One of the most compelling factors driving the gene therapy market is the rising prevalence of genetic disorders and chronic conditions. Diseases such as cystic fibrosis, sickle cell anaemia, and certain cancers are often untreatable with conventional therapies. Gene therapy provides a novel approach to address these diseases at the molecular level, offering potential cures. The increasing incidence of these conditions has spurred significant investment in research and development, particularly in targeting rare diseases. This focus has also led to more clinical trials and approvals, with governments and organizations supporting innovation through funding and incentives. For example, regulatory frameworks like the FDA's accelerated approval pathway are enabling quicker market access for therapies that address unmet medical needs, further driving the adoption and commercialization of gene therapies.
Technological Advancements Transforming the Gene Therapy Landscape
The integration of advanced technologies, particularly CRISPR-Cas9 and other gene-editing tools, is revolutionizing the field of gene therapy. These technologies enable precise and efficient editing of the genome, allowing scientists to directly target genetic mutations with high accuracy. Furthermore, advancements in delivery systems, such as viral vectors like adeno-associated viruses (AAV) and non-viral methods like lipid nanoparticles, have improved the safety and efficacy of gene therapies. Another transformative advancement is the application of AI in gene therapy development. AI is enhancing the discovery process, optimizing vector design, and accelerating clinical trial success rates. These advancements are making gene therapy more accessible, scalable, and tailored to individual patients, thereby positioning the market for sustained growth in the coming years.
To learn more about this report, download the PDF brochure
Competitive Landscape Analysis
The global gene therapy market features both established and emerging players, including Amgen Inc.; Novartis AG; F. Hoffmann-La Roche; Gilead Sciences, Inc.; bluebird bio, Inc.; Bristol-Myers Squibb Company; Legend Biotech; BioMarin; uniQure N.V.; Merck & Co.; Sarepta Therapeutics, Inc.; Krystal Biotech, Inc. and CRISPR Therapeutics among others. Some of the key strategies adopted by market players include product innovation and development, strategic partnerships and collaborations, and geographic expansion.
Report Scope
| Report Metric | Details |
| Base Year Considered | 2023 |
| Historical Data | 2022 – 2023 |
| Forecast Period | 2024 – 2029 |
| Growth Rate | CAGR of 20% |
| Market Drivers |
|
| Attractive Opportunities |
|
| Segment Scope | Type, Vector, Therapeutic Area and Route of Administration |
| Regional Scope |
|
| Key Companies Mapped | AG; F. Hoffmann-La Roche; Gilead Sciences, Inc.; bluebird bio, Inc.; Bristol-Myers Squibb Company; Legend Biotech; BioMarin; uniQure N.V.; Merck & Co.; Sarepta Therapeutics, Inc.; Krystal Biotech, Inc. and CRISPR Therapeutics |
| Report Highlights | Market Size & Forecast, Growth Drivers & Restraints, Trends, Competitive Analysis |
Global Gene Therapy Market Segmentation
This report by Medi-Tech Insights provides size of the gene therapy market at the regional- and country-level from 2022 to 2029. The report further segments the market on the basis of type, vector, therapeutic area and route of administration
- Market Size & Forecast (2022-2029), By Type, USD Million
- Gene Silencing
- Cell Replacement
- Gene Augmentation
- Other Therapies
- Market Size & Forecast (2022-2029), By Vector, USD Million
- Viral Vectors
- Non-viral Vectors
- Market Size & Forecast (2022-2029), By Therapeutic Area, USD Million
- Neurology
- Oncology
- Hepatology
- Other Therapeutic Areas
- Market Size & Forecast (2022-2029), By Route of Administration, USD Million
- Intravenous
- Others
- Market Size & Forecast (2022-2029), By Region, USD Million
- North America
- US
- Canada
- Europe
- UK
- Germany
- France
- Italy
- Spain
- Rest of Europe
- Asia Pacific
- China
- India
- Japan
- Rest of Asia Pacific
- Latin America
- Middle East & Africa
- North America
Key Strategic Questions Addressed
- What is the market size & forecast of the gene therapy market?
- What are historical, present, and forecasted market shares and growth rates of various segments and sub-segments of the gene therapy market?
- What are the key trends defining the market?
- What are the major factors impacting the market?
- What are the opportunities prevailing in the market?
- Which region has the highest share in the global market?
- Which region is expected to witness the highest growth rate in the next 5 years?
- Who are the major players operating in the market?
- What are the key strategies adopted by players?
- Introduction
- Introduction
- Market Scope
- Market Definition
- Segments Covered
- Regional Segmentation
- Research Timeframe
- Currency Considered
- Study Limitations
- Stakeholders
- List of Abbreviations
- Key Conferences and Events (2023-2024)
- Research Methodology
- Secondary Research
- Primary Research
- Market Estimation
- Bottom-Up Approach
- Top-Down Approach
- Market Forecasting
- Executive Summary
- Gene Therapy Market Snapshot (2023-2029)
- Segment Overview
- Regional Snapshot
- Competitive Insights
- Market Overview
- Market Dynamics
- Drivers
- Increasing prevalence of genetic disorders and chronic diseases
- Advancements in gene-editing technologies such as CRISPR-Cas9
- Rising investment in R&D and clinical trials for novel therapies
- Supportive regulatory frameworks and expedited approval pathways
- Growing demand for personalized medicine
- Restraints
- High costs of gene therapy treatments
- Safety concerns related to long-term effects and immune responses
- Limited patient awareness and accessibility in developing regions
- Opportunities
- Expansion of gene therapy applications to treat common and rare diseases
- Shift toward decentralized manufacturing to ensure faster production and accessibility
- Key Market Trends
- Adoption of CRISPR-Cas9 and other advanced gene-editing technologies
- Utilization of AI and M/L to optimize therapy development and clinical trials
- Unmet Market Needs
- Industry Speaks
- Regulatory Analysis
- Drivers
- Market Dynamics
- Global Gene Therapy Market Size & Forecast (2022-2029), By Type, USD Million
- Introduction
- Gene Silencing
- Cell Replacement
- Gene Augmentation
- Other Therapies
- Global Gene Therapy Market Size & Forecast (2022-2029), By Vector, USD Million
- Introduction
- Viral Vectors
- Non-viral Vectors
- Global Gene Therapy Market Size & Forecast (2022-2029), By Therapeutic Area, USD Million
- Introduction
- Neurology
- Oncology
- Hepatology
- Other Therapeutic Areas
- Global Gene Therapy Market Size & Forecast (2022-2029), By Route of Administration, USD Million
- Introduction
- Intravenous
- Others
- Global Gene Therapy Market Size & Forecast (2022-2029), By Region, USD Million
- Introduction
- North America Gene Therapy Market Size & Forecast (2022-2029), By Country, USD Million
- US
- Market Size & Forecast, By Type (USD Million)
- Market Size & Forecast, By Vector (USD Million)
- Market Size & Forecast, By Therapeutic Area (USD Million)
- Market Size & Forecast, By Route of Administration (USD Million)
- Canada
- Market Size & Forecast, By Type (USD Million)
- Market Size & Forecast, By Vector (USD Million)
- Market Size & Forecast, By Therapeutic Area (USD Million)
- Market Size & Forecast, By Route of Administration (USD Million)
- US
- Europe Gene Therapy Market Size & Forecast (2022-2029), By Country, USD Million
- UK
- Market Size & Forecast, By Type (USD Million)
- Market Size & Forecast, By Vector (USD Million)
- Market Size & Forecast, By Therapeutic Area (USD Million)
- Market Size & Forecast, By Route of Administration (USD Million)
- Germany
- Market Size & Forecast, By Type (USD Million)
- Market Size & Forecast, By Vector (USD Million)
- Market Size & Forecast, By Therapeutic Area (USD Million)
- Market Size & Forecast, By Route of Administration (USD Million)
- France
- Market Size & Forecast, By Type (USD Million)
- Market Size & Forecast, By Vector (USD Million)
- Market Size & Forecast, By Therapeutic Area (USD Million)
- Market Size & Forecast, By Route of Administration (USD Million)
- Italy
- Market Size & Forecast, By Type (USD Million)
- Market Size & Forecast, By Vector (USD Million)
- Market Size & Forecast, By Therapeutic Area (USD Million)
- Market Size & Forecast, By Route of Administration (USD Million)
- Spain
- Market Size & Forecast, By Type (USD Million)
- Market Size & Forecast, By Vector (USD Million)
- Market Size & Forecast, By Therapeutic Area (USD Million)
- Market Size & Forecast, By Route of Administration (USD Million)
- Rest of Europe
- Market Size & Forecast, By Type (USD Million)
- Market Size & Forecast, By Vector (USD Million)
- Market Size & Forecast, By Therapeutic Area (USD Million)
- Market Size & Forecast, By Route of Administration (USD Million)
- UK
- Asia Pacific (APAC) Gene Therapy Market Size & Forecast (2022-2029), By Country, USD Million
- China
- Market Size & Forecast, By Type (USD Million)
- Market Size & Forecast, By Vector (USD Million)
- Market Size & Forecast, By Therapeutic Area (USD Million)
- Market Size & Forecast, By Route of Administration (USD Million)
- Japan
- Market Size & Forecast, By Type (USD Million)
- Market Size & Forecast, By Vector (USD Million)
- Market Size & Forecast, By Therapeutic Area (USD Million)
- Market Size & Forecast, By Route of Administration (USD Million)
- India
- Market Size & Forecast, By Type (USD Million)
- Market Size & Forecast, By Vector (USD Million)
- Market Size & Forecast, By Therapeutic Area (USD Million)
- Market Size & Forecast, By Route of Administration (USD Million)
- Rest of Asia Pacific
- Market Size & Forecast, By Type (USD Million)
- Market Size & Forecast, By Vector (USD Million)
- Market Size & Forecast, By Therapeutic Area (USD Million)
- Market Size & Forecast, By Route of Administration (USD Million)
- China
- Latin America (LATAM) Gene Therapy Market Size & Forecast (2022-2029), USD Million
- Market Size & Forecast, By Type (USD Million)
- Market Size & Forecast, By Vector (USD Million)
- Market Size & Forecast, By Therapeutic Area (USD Million)
- Market Size & Forecast, By Route of Administration (USD Million)
- Middle East & Africa (MEA) Gene Therapy Market Size & Forecast (2022-2029), USD Million
- Market Size & Forecast, By Type (USD Million)
- Market Size & Forecast, By Vector (USD Million)
- Market Size & Forecast, By Therapeutic Area (USD Million)
- Market Size & Forecast, By Route of Administration (USD Million)
- Competitive Landscape
- Key Players and their Competitive Positioning
- Key Player Comparison
- Segment-wise Player Mapping
- Market Share Analysis (2023)
- Company Categorization Matrix
- Dominants/Leaders
- New Entrants
- Emerging Players
- Innovative Players
- Key Strategies Assessment, By Player (2022-2024)
- New Product Launches
- Partnerships, Agreements, & Collaborations
- Mergers & Acquisitions
- Geographic Expansion
- Key Players and their Competitive Positioning
- Company Profiles*
(Business Overview, Financial Performance**, Products Offered, Recent Developments)
- Amgen Inc.
- Novartis AG
- Hoffmann-La Roche
- Gilead Sciences, Inc.
- bluebird bio, Inc.
- Bristol-Myers Squibb Company
- Legend Biotech
- BioMarin
- uniQure N.V.
- Sarepta Therapeutics, Inc.
- Other Prominent Players
The study has been compiled based on extensive primary and secondary research.
Secondary Research (Indicative List)
Primary Research
To validate research findings (market size & forecasts, market segmentation, market dynamics, competitive landscape, key industry trends, etc.), extensive primary interviews were conducted with both supply and demand-side stakeholders.
Supply Side Stakeholders:
- Senior Management Level: CEOs, Presidents, Vice-Presidents, Directors, Chief Technology Officers, Chief Commercial Officers
- Mid-Management Level: Product Managers, Sales Managers, Brand Managers, R&D Managers, Business Development Managers, Consultants
Demand Side Stakeholders:
- Biotechnology and Pharmaceutical Companies, Academic & Research Institutes and Others
Breakdown of Primary Interviews
Market Size Estimation
Both ‘Top-Down & Bottom-Up Approaches’ were used to derive market size estimates and forecasts
Data Triangulation
Research findings derived through secondary sources & internal analysis was validated with Primary Interviews, Internal Knowledge Repository and Company’s Sales Data
