Global Renal Denervation Market Size, Share, Growth, Trends and Analysis by 2027

Global Renal Denervation Market Size, Share, Growth, Trends and Analysis by 2027

Global Renal Denervation Market Size, Share, Growth, Trends and Analysis by 2027

Global Renal Denervation Market estimated at $140 Million (2022), is growing at a healthy CAGR of 40% y 2027. The market growth is driven by the growing geriatric population, the rising prevalence of hypertension, and venture capital funding. The U.S. market is likely to offer high growth opportunities in next 3-5 years.

Resistant hypertension is a blood pressure that remains elevated above target levels despite use of anti-hypertensive medications. About 12-15% of the population treated for high blood pressure suffers from resistant hypertension. Renal denervation is a minimally invasive procedure used to treat resistant hypertension. As the geriatric population is growing, the number of people suffering from hypertension and the resistant hypertension is also growing which is driving the RDN market growth.

The rising prevalence of hypertension is driving the Renal Denervation Market Growth

According to WHO, currently more than one billion people across the globe are suffering from hypertension which is expected to grow to 1.6 billion by 2025. WHO estimated that less than one in five people have their hypertension under control, either due to non-adherence or resistance to medications. This is leading to growing prevalence of hypertension/resistant hypertension, thereby driving the Renal Denervation market growth.

Lack of long-term clinical data and risks associated with RDN procedure inhibits the Renal Denervation market growth

Though Renal Denervation is perceived as potential treatment for resistant hypertension, it is a relatively new procedure and less data is available on its long-term effects. Owing to the limited clinical evidence, the RDN products are available only for investigational purpose in some of the major markets. For instance, Medtronic’s Symplicity Spyral RDN System’s use is limited only to investigational purpose in the U.S., Japan, and Canada. Further, there are various risks associated with this procedure which limits its use. Some patients experience bradycardia during the procedure. The RF ablation may cause changes to the wall of the arteries, which can sometimes lead to renal artery stenosis. The imaging used during the procedure also has a number of risks. Other complications include tearing in the renal arteries and pseudoaneurysm (a bruise caused by a leaking hole in an artery).

North America to offer high growth opportunities in Renal Denervation Market

From a geographic perspective, Europe is the single largest renal denervation market. This is mainly attributed to the growing aging population, rising prevalence of hypertension, and higher penetration due to commercial availability of RDN products within Europe. The North American market is at nascent stage as the RDN companies are yet to launch the products for commercial use in the region. However, the companies in the RDN market are thriving to introduce their products in the U.S. market and are focusing their efforts on getting the commercial approvals. For instance, Medtronic is likely to publish its results of SPYRAL HTN-ON MED clinical trials for its RDN system in the U.S. in later half of 2022. Further, in March 2022, ReCor Medical (Otsuka) completed subject enrolment for its RADIANCE-II pivotal trial of its Paradise Ultrasound Renal Denervation (uRDN) System for generating clinical trial data to enter the U.S. market.

Some key players operating in the global renal denervation market include Medtronic, Boston Scientific Corporation, St. Jude Medical (Abbott), ReCor Medical (Otsuka), Cordis Corporation, and Terumo Corporation, among others.

Citing the growth potential of Renal Denervation Market, venture capital firms are helping start-ups to expedite their clinical trial efforts

  • In December 2021, SyMap Medical completed financing round of $100 million led by Primavera Capital and VMS Group, with the participation of existing investors Simiao Equity Investment and Sequoia Capital China.
  • In April 2021, China-based renal denervation firm Brattea completed $20 million funding round. The round was led by led by healthcare private equity fund Kuanping Capital.

Key Strategic Questions Addressed

  • What is the market size & forecast of Renal Denervation market?
  • What are historical, present, and forecasted market shares and growth rates of various segments and sub-segments of Renal Denervation market?
  • What are the key trends defining the Renal Denervation market?
  • What are the major factors impacting the RDN market?
  • What are the opportunities prevailing in the Renal Denervation market?
  • Which region has the highest share in the global RDN market? Which region is expected to witness highest growth rate in the next 5 years?
  • Who are the end users of the RDN products?
  • Who are the major players operating in the Renal Denervation market?
  • Who are the new players entering the Renal Denervation market?
  • What are the key strategies adopted by RDN market players?

The study has been compiled based on the extensive primary and secondary research.

Secondary Research (Indicative List)

Renal Denervation Market

Primary Research

To validate research findings (market size & forecasts, market segmentation, market dynamics, competitive landscape, key industry trends, etc.), extensive primary interviews were conducted with both supply and demand side stakeholders.

Supply Side Stakeholders:

  • Senior Management Level: CEOs, Presidents, Vice-Presidents, Directors, Chief Technology Officers, Chief Commercial Officers
  • Mid-Management Level: Product Managers, Sales Managers, Brand Managers, R&D Managers, Business Development Managers, Consultants


Demand Side Stakeholders:

  • Stakeholders in hospitals, catheterization laboratory etc.


Breakdown of Primary Interviews

Renal Denervation Market

Market Size Estimation

The market size was derived based on extensive secondary research further validated through expert interviews.

Data Triangulation

Research findings derived through secondary sources & internal analysis was validated with primary interviews, and internal knowledge repository.

Renal Denervation Market

Renal Denervation Market