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Stem Cell Therapy Market – Disruptive Medical Therapy of the Future

written by Medi-Tech Insights, Friday, October 29th, 2021

The Global Stem Cell Therapy Market valued at ~$200 million (2021) is set to witness healthy
growth rate of 17% in the next 5 years. Favorable investment environment, rising clinical trials for
stem cell based-therapies, increasing demand for induced pluripotent stem cells (iPSCs) as an
alternative to embryonic stem cells (ESCs) and the growing demand for cell & gene therapies are
some of the key factors driving the Global Stem Cell Therapy Market.


Derivation of embryonic stem cells (ESCs) requires destruction of human embryos. Ethical concerns
related to embryonic stem cells is one the of key factors that is likely to hamper the growth of the
market. Increasing number of clinics offering unproven stem cell-based treatments is another
ethical issue faced in the field of stem cell-based therapies.

DESCRIPTION

Stem cells are the body’s raw materials. They are unspecialized cells that have ability to renew themselves through mitotic cell division and differentiate into a diverse range of specialized cell types. They are critical for the development, growth, maintenance and repair of bones, muscles, blood, brain, nerves, skin and other organs.  There are several sources of stem cells:

  • Embryonic Stem Cells: These stem cells come from embryos that are three to five days old. These are pluripotent stem cells and can be used to regenerate or repair diseased tissues and organs
  • Adult Stem Cells: These stem cells are found in most adult tissues (bone marrow or fat) in small numbers. As compared to embryonic stem cells, they have more limited ability to give rise to various cells of the body
  • Induced Pluripotent Stem Cells: Using genetic reprogramming, adult cells are transformed by scientists into stem cells that act similar to embryonic stem cells
  • Perinatal Stem Cells: These stem cells are found in amniotic fluid & umbilical cord blood. They have the ability to change into specialized cells.

 

Factors Igniting Interest in Stem Cells

  • To Develop Understanding of How Diseases Occur: By observing how stem cells mature into cells in nerves, bones, heart muscles and other organs and tissues, researchers and healthcare professionals may better understand how diseases and conditions develop
  • Help in Generating Healthy Cells to Replace Diseased Cells: Stem cells possess the potential to transform into specific cells that can be used to regenerate and repair diseased or damaged tissues
  • To Test Safety and Effectiveness of  New Drugs: Prior to using investigational drugs on people, researchers can use stem cells to test drugs for quality & safety

 

Transplantation of Blood Stem Cells Most Established Stem Cell Treatment

Currently, there are only limited stem cell therapies that have been thoroughly established as safe and effective treatment. The most well-established and widely used stem cell treatment is the transplantation of blood stem cells to treat diseases and conditions of the blood and immune system, or to restore the blood system after treatments for specific cancers.

Other areas/indications where stem cell therapies are being used are:

  • For the treatment of knee cartilage defects in patients with Osteoarthritis (OA)
  • For the treatment of Crohn’s fistula
  • For regeneration of subcutaneous adipose tissue
  • For the treatment of ALS (Amyotrophic Lateral Sclerosis)
  • For the treatment of acute graft versus host disease (aGVHD) in children and adults
  • For the treatment of limbal stem cell deficiency (LSCD)
  • For the treatment of Critical Limb Ischemia (CLI), among others

 

“Stem cells have a bright future for the therapeutic world by promising stem cell therapy. We hope to see new horizon of therapeutics in the form of bone marrow transplant, skin replacement, organ development, and replacement of lost tissue such as hairs, tooth, retina and cochlear cells.”

CEO, South Korea Based Stem Cell Therapy Provider 

 

Competitive Landscape

Some of the key players operating in the market are JCR Pharmaceuticals, MEDIPOST, Takeda Pharmaceutical Company, PHARMICELL, Smith & Nephew, Anterogen, AlloSource, Holostem Terapie Avanzate S.r.l, Regrow Biosciences, CORESTEM, Stempeutics Research (India)., among others.

 

Company with Pipeline Products (Indicative List)

  • Athersys
  • BioRestorative Therapies
  • BrainStorm Cell Therapeutics
  • Cellular Biomedicine Group
  • Hope Biosciences
  • Kangstem Biotech
  • Mesoblast
  • Personalized Stem Cells
  • Pluristem Therapeutics
  • ViaCyte

 

Future Outlook

Stem cell therapy could be the medical innovation of the century. It has emerged as a promising new approach in almost every medicine specialty. Despite an enormous amount of research being undertaken, there are still limited safe and effective treatments available to patients. This is partially because complex diseases which are currently incurable require complex treatments and a personalised approach.

However, the future prospects of stem cell therapy looks promising as there are several ongoing and completed clinical trials involving stem cells which are showcasing positive outcomes.

In clinical studies and treatment attempts, stem cell therapies have been tested with the following indications:

  • Macular Degeneration
  • Neurological Conditions
  • Diabetes
  • Graft-versus-host disease (GvHD)
  • Spinal Cord Injury
  • Myocardial Infarction
  • Autoimmune Diseases
  • Autism
  • Hearing Loss
  • HIV
  • Cirrhosis of the Liver, among others

 

Stem cell therapies are increasingly being seen as the transformative step in treating conditions with unmet needs. This, coupled with growing investment in the sector and an increasing number of stem cell donors is expected to drive the market forward in the coming years.

TABLE OF CONTENTS

Key Strategic Questions Addressed

 

  • What is the market size & forecast of Stem Cell Therapy Market?
  • What are historical, present, and forecasted market shares and growth rates of various segments and sub-segments of Stem Cell Therapy Market?
  • How is the funding landscape of Stem Cell Therapy Market?
  • What are the key trends defining the market?
  • What are the major factors impacting the market?
  • What are the opportunities prevailing in the market
  • What are the key applications of Stem Cell Therapy Market?
  • Which region has the highest share in the global market? Which region is expected to witness highest growth rate in the next 5 years?
  • Who are the major players operating in the market?
  • Who are the new players entering the market?
  • What are the key strategies adopted by players?

METHODOLOGY

The study has been compiled based on the extensive primary and secondary research.

 

Primary Research

To validate research findings (market size & forecasts, market segmentation, market dynamics, competitive landscape, key industry trends, etc.), extensive primary interviews were conducted with both supply and demand side stakeholders.

Supply Side Stakeholders

  • CEOs, Presidents, Vice-Presidents, Directors, Chief Technology Officers, Chief Commercial Officers
  • Product Managers, Sales Managers, Brand Managers, R&D Managers, Business Development Managers, Consultants

 

Demand Side Stakeholders

  • Stakeholders in Academic & Research Institutes, Pharmaceutical & Biotechnology Companies, Clinical Laboratories, Hospitals and Other End Users

 

Breakdown of Primary Interviews

Market Size Estimation

Both ‘Top-Down and Bottom-Up Approaches’ were used to derive market size estimates and forecasts

Data Triangulation

Research findings derived through secondary sources & internal analysis was validated with Primary Interviews, Internal Knowledge Repository and Company’s Sales Data

SAMPLE DELIVERABLES

 


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